Well, a guide on SP is gonna leave SP the same time either way, and you'll get the same time in fishing whether you left SP with him or he picks you up on CC. I'm partial to Long Caye, but you've got other options out of SP or CC if you're trying to cut the "ride" down. Hick's Caye to the west off CC can be good. Also the south and west sides of Congrejo. Some big fish at the mainland river mouths due west of SP, and you can run through Savannah on the way to/fro. Mainland is only about 1/2 the trip Long Caye is.
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Flyfishing my way through mid-life crisis.