We just returned from our first trip to Belize and Portofino -- we cannot wait to go back...like everyone else who visits we are going through withdrawal...
Portofino is at the far north end of the island and is beautiful...we stayed in one of the treetop suites and our only (small) complaint is that the view of the caribbean from the porch is partially blocked by the beach cabanas which sit directly on the beach in front of the suite (which is raised up on stilts - since you pay more for this much larger suite, you would think the view would be better than that of the less expensive room!) ANYHOW, besides that NO COMPLAINTS here...the bartender, Jamal, was new, enthusiastic and fun, we ate there a few times and the food was good, the owners and the rest of the staff were really helpful and accomodating.
Our favorite restaurant was Capricorn - the stuffed grouper was awesome and the owner, Annabelle was friendly and a lot of fun - so much so we went twice in six nights! Loved Fido's but other than that, didn't really spend much time in San Pedro itself - we were there to relax and spend some time together, and Portofino's location is perfect for that.
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Have a great time!