Geez, Daylon, I go everywhere at all hours, often by myself. I'm not saying that is all that smart though.
(oh yeah, and I'm rarely on the south side unless you call Playador or Iguana's south side)
Use your common sense. Treat the locals with respect. And if you are getting little warning bells going off in your head, heed them.
Also, if you see a fight break out or about to break out between locals, don't try to intervene or even stay and watch. Get the hell out of there and fast.