LBI, There probably are different size bottles, but I have a 4oz dose. Not sure how many applications you can get, I guess it would depend on how thick you put it on. Instructions say "apply liberally to ARMS & LEGS, and all exposed areas 10 minutes before entering water." I'd say if you're there for a couple weeks and plan on using it everyday you'll need a couple bottles. Sounds as if spending a few extra bucks on a bottle could be well worth the expense. cool Karen